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LECO offers an extensive library of Application Notes that showcase the performance of our instruments in fields such as food testing, environmental analysis, energy, agriculture, materials science, and more. These documents provide practical insights into sample preparation, method optimization, and instrument capabilities, so users can see exactly how LECO technology addresses their unique testing needs.
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Application Notes are detailed, real-world examples of how analytical instruments are used to solve common laboratory challenges. Each note demonstrates methods, workflows, and results across a wide range of industries, helping scientists and researchers understand how to achieve accurate, reproducible data with confidence.
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Chemical Profiling of Commercially Available Cola Beverages Using GC-TOFMS and ChromaTOF Sync
203-821-712In this study, HS-SPME was used to extract the Volatile Organic Compounds (VOCs) of 13 commercially available cola beverages for analysis by GC-TOFMS. The data were then processed using our data alignment tool ChromaTOF Sync, which compiles peak information through sets of samples by performing automated peak finding and deconvolution...Access Chemical Profiling of Commercially Available...Sensory-Directed Analysis for Beer Aroma Profiling: Stacking Multiple SPME Extractions to Help Connect Olfactory and GC-MS Data
203-821-711This application note highlights how stacking multiple SPME extractions with GC-MS and GC-Olfactory can improve detection of low-level analytes in complex samples, such as beer, allowing researchers to identify compounds that might otherwise go unnoticed. It demonstrates the value of sensitive techniques for revealing impactful analytes that contribute to aroma...Access Sensory-Directed Analysis for Beer Aroma Profiling...Packaging Contaminants in the Headspace of Commercially Available Cola Beverages
203-821-710This application note explores the analysis of packaging-derived contaminants in the headspace of commercially available cola beverages using GC×GC-TOFMS with ChromaTOF Sync. The study focuses on identifying volatile organic compounds (VOCs) that may migrate from packaging materials into the beverage, potentially affecting quality, safety, and regulatory compliance. Using comprehensive two-dimensional...Access Packaging Contaminants in the Headspace...Determination of Carbon Black in Polypropylene
203-821-709National and regional regulations provide guidance on the approved grade and type of Carbon Black, and some regulations specifically restrict the amount of Carbon Black that may be present in plastics designated for food contact. A common method for determining the content of Carbon Black in polymer materials is thermogravimetric...Access Determination of Carbon Black in...Characterization of Extractables from Dental Bite Guards Using GC-TOFMS
203-821-708This application note details the characterization of extractable compounds from dental bite guards using high-resolution time-of-flight mass spectrometry (HRT-TOFMS) with GC×GC and ChromaTOF software. Materials used in dental devices may release chemical compounds over time, raising concerns about patient safety and material performance. The study demonstrates how comprehensive two-dimensional gas...Access Characterization of Extractables from Dental...Improved GCxGC-TOFMS Workflow to More Efficiently Meet Compliance and Confidence Requirements for Fragrance Allergen Analysis
203-821-707This application note presents an improved workflow for the analysis of fragrance allergens using comprehensive two-dimensional gas chromatography (GC×GC) coupled with time-of-flight mass spectrometry (TOFMS). With increasing regulatory pressure on labeling and quantifying fragrance allergens in personal care and consumer products, sensitive and robust analytical methods are essential. The study...Access Improved GCxGC-TOFMS Workflow to More...Determination of Ash in Various Plastics and Plastic Blends
203-821-704Determining the filler content of plastic is an important aspect of quality control monitoring. Ash is the inorganic remainder that is left after heating a polymer at high temperatures to remove the presence of water and organic matter. Therefore, the ash content of a plastic is reflective of the relative...Access Determination of Ash in Various...Analysis of Musty Odorous Compounds in Drinking Water by SPME GC-TOFMS
203-821-703Complaints received by drinking water industries are often related to bad taste and/or unpleasant odors in drinking water. Most complaints involve the presence of chlorine or earthy/musty-smelling compounds. These issues can lead consumers to perceive the water as "unsafe", even though the substances causing the issues are typically not harmful....Access Analysis of Musty Odorous Compounds...Quantitation of Olefin Content in Plastic-Derived Pyrolysis Oils – QuadJet SD
203-821-697This application note focuses on the quantitation of olefin content in plastic-derived pyrolysis oils using GC×GC-FID with the LECO QuadJet SD system and ChromaTOF Tile. Accurate identification and measurement of olefins are critical for evaluating pyrolysis oil quality and refining potential. The method combines comprehensive two-dimensional gas chromatography with flame...Access Quantitation of Olefin Content in...Determination of Nitrogen in Plastics
203-821-669The determination of Nitrogen is crucial in the material characterization and quality control procedures for the manufacturing and molding process of plastic materials. The LECO FP928 is a Nitrogen determinator that utilizes an automated Dumas combustion method and provides accurate and precise results in approximately five minutes. This eliminates...Access Determination of Nitrogen in PlasticsSatisfying ASTM D8396 Requirements Paradigm GCxGC-FID
203-821-696This application note describes how to use a simple workflow with the LECO Paradigm system to fulfill the requirements of the ASTM D8396 test method to quantitatively determine mass % of total n-paraffins, iso-paraffins, naphthenes, 1-ring aromatics, and 2-ring aromatics using reverse-fill flush flow modulated comprehensive two-dimensional gas chromatography–flame ionization...Access Satisfying ASTM D8396 Requirements Paradigm...Ginger Oil Analysis and Grade Differentiation with Pegasus BTX Using Hydrogen Carrier Gas
203-821-694Ginger Oil Analysis and Grade Differentiation with Pegasus BTX Using Hydrogen Carrier GasAccess Ginger Oil Analysis and Grade...Determination of Ash in Polystyrene
203-821-693Determination of Ash in PolystyreneAccess Determination of Ash in PolystyreneDetermination of Ash in Polyethylene
Determination of Ash in Polypropylene